Feature Detail
xfine pyhsician

Turn information into insight

xFine gives you the ability to visualize small lesions down to 2 mm. So you have the information you need to make clinically relevant decisions.

Closing in on the fine details

Smaller image voxels can have a significant impact on clinical decisions. ×Fine is a 2 mm whole-body clinical reconstruction protocol offering superb spatial resolution. It helps you draw regions of interest around small structures with increased confidence. The smaller voxels reduce partial-volume effects, resulting in enhanced quantification accuracy and lesion detectability.

xfine magnifier

More detail from one image

xfine 4mm scan

Image courtesy of Salzburg University Hospital, Austria

These whole-body scans were reconstructed from the same data using a 4 mm voxel size (left), ×Fine (center), and ×Fine plus ×Sharp (right). The improved detail can be seen with ×Fine plus xSharp.

xFine in clinical practice

In a recent paper, specialists reported a case study of a 68-year-old woman with lung cancer, being investigated for possible metastases in the adrenal gland. On the image reconstructed using 4 mm voxels, there was no enlargement of the gland on CT, and there was a slightly increased FDG uptake. This led the clinicians to consider the gland to be benign. On a retrospective image reconstruction using 2 mm voxels, there was a higher SUVmax and a higher contrast (despite increased noise). The gland appeared suspicious and more likely to be metastatic. A follow-up PET/CT scan two months later revealed an even higher SUVmax and an enlarged right adrenal gland.

*Koopman D, van Dalen J, Jager P. Improved detection of a metastatic adrenal gland using FDG-PET with small voxels. Tijdschrift vood Nucleaire Geneeskunde. 2014; 36(3): 1279

xfine infographic
youtube image v6

See it for yourself

Experts at Isala Hospital have adopted image reconstruction using 2 mm voxels as standard. Tune in to the video to find out why.

All our nuclear medicine physicians now favor small voxel reconstructions and even wait with releasing final reports until they have reviewed the ×Fine reconstructed images. The main advantage is excellent detectability of small lesions. Although difficult to quantify, the lesion delineation increases the confidence of reading. Also, we have the strong impression that small lesions are now detectable.”

Prof. Dr. Piet Jager, MD, PhD

Nuclear medicine specialist, Isala Hospital, Zwolle, the Netherlands


Want to learn more about how research and clinical routines can benefit from xFine and the entire xPand5 technology suite?

xfine brochure

Discover the value 2 mm reconstruction with ×Fine brings to Isala Hospital in the Netherlands.

xfine article

To find out more and gain answers to your open questions, please get in touch.


Contact information

* This field is mandatory


By specifying your reason for contact we will be able to provide you with a better service.

We work with partners and distributors who may contact you about this Philips product on our behalf.


Final CEE consent

You are about to visit a Philips global content page

You are about to visit the Philips USA website.

Our site can best be viewed with the latest version of Microsoft Edge, Google Chrome or Firefox.